The link thr777 Diaries

This benefit is calculated by NCBI based upon knowledge from submitters. Examine our regulations for calculating the assessment status. The volume of submissions which add to this evaluation status is demonstrated in parentheses.

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The issue for your classification, furnished by the submitter for this submitted (SCV) file. This column also includes the influenced status and allele origin of individuals noticed with this particular variant.

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The number of variants in ClinVar which can be contained within just this gene, which has a link to view the listing of variants.

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The influence with the variant on RNA or protein purpose, dependant on experimental proof from submitters.

This sequence improve has an effect on codon 777 of the GAA mRNA. It is a 'silent' adjust, indicating that it does not change the encoded amino acid sequence from the login thr777 GAA protein. This variant also falls at the last nucleotide of exon sixteen, and that is Component of the consensus splice web-site for this exon. This variant is current in population databases (rs375311693, gnomAD 0.03%). This variant has not been documented from the literature in persons influenced with GAA-similar disorders.

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